CAS:868-54-2 | 2-AMINO-1-PROPENE-1,1,3-TRICARBONITRILE

Introduction of CAS:868-54-2 | 2-AMINO-1-PROPENE-1,1,3-TRICARBONITRILE

2-Amino-1-propene-1,1,3-tricarbonitrile is a chemical compound that has drawn interest due to its potential applications in various fields of chemistry, including organic synthesis and material science. It serves as a precursor for the synthesis of diverse heterocyclic compounds, which are valuable in pharmaceuticals, agrochemicals, and dyestuffs.

The synthesis of compounds related to 2-Amino-1-propene-1,1,3-tricarbonitrile involves multi-component reactions that allow the efficient assembly of complex structures from simple precursors. For instance, a related approach was used to synthesize 2-amino-4-(2, 5-dimethoxyphenyl)-4a,5,6,7-tetrahydronaphthalene-1,3,3(4H)-tricarbonitrile through conventional spectroscopic techniques and X-ray diffraction studies, highlighting the versatility of amino carbonitriles in constructing cyclic and acyclic structures with potential biological activity (Sharma et al., 2022).

Specification of CAS:868-54-2 | 2-AMINO-1-PROPENE-1,1,3-TRICARBONITRILE

Research Application of CAS:868-54-2 | 2-AMINO-1-PROPENE-1,1,3-TRICARBONITRILE

Antitumor Activities

2-Amino-1-propene-1,1,3-tricarbonitrile has been utilized as a precursor in synthesizing quinoline, furan, pyrazole, and thiophene derivatives, which demonstrated significant antitumor activities against various cancer cell lines, such as breast adenocarcinoma, non-small cell lung cancer, and CNS cancer. Some of these synthesized compounds have shown high inhibitory effects in cancer treatments (Mohareb, Fleita, & Sakka, 2011).

Synthesis of Heterocyclic Systems

This chemical serves as a multifunctional reagent widely used in the preparation of diverse heterocyclic systems, playing a key role in organic synthesis. The majority of the applications in this area have been explored in the last 20-25 years, highlighting its relevance in modern chemistry (Dotsenko, Krivokolysko, & Semenova, 2018).

Corrosion Inhibition

Studies have shown that derivatives of 2-Amino-1-propene-1,1,3-tricarbonitrile can act as effective corrosion inhibitors for mild steel in acidic environments. These compounds are reported to provide protective films on the mild steel surface, significantly reducing corrosion rates (Verma, Quraishi, & Singh, 2015).

Solvatochromic Behavior

Research has demonstrated the solvatochromic properties of derivatives of 2-Amino-1-propene-1,1,3-tricarbonitrile, indicating their potential as solvatochromic probes. These studies explore the interaction of these compounds with different solvents and their ability to indicate changes in solvent polarity (Elmsheeti, Hemdan, Sammour, & Alnajjar, 2020).

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