Introduction and application of CAS No.139756-01-7 | 1-Methyl-4-nitro-3-propylpyrazole-5-carboxamide
1-Methyl-4-nitro-3-propylpyrazole-5-carboxamide is an impurity of sildenafil, which is used as a treatment for erectile dysfunction. It has been found in the environment due to its widespread use and it can be detected using chromatographic methods.
1-Methyl-4-nitro-3-propylpyrazole-5-carboxamide binds to thiol groups and may cause male infertility in animals. The detection time for this compound ranges from 2 hours to 24 hours, depending on the detection method. This impurity also has fluorescence properties that can be detected with UV light.
Synonyms:
2-methyl-4-nitro-5-propylpyrazole-3-carboxamide;
1H-Pyrazole-5-carboxamide,1-methyl-4-nitro-3-propyl;
1-Methyl-4-nitro-3-propyl-(1H)-pyrazole-5-carboxamide;
1-methyl-4-nitro-3-propyl-1H-5-pyrazole carboxamide;
1-methyl4-nitro-3-n-propylpyrazole-5-carboxamide;
1-Methyl-4-nitro-3-propylpyrazole-5-carboxamide;
2-methyl-4-nitro-5-propyl-2H-pyrazole-3-carboxamide;
Specification of CAS No.139756-01-7 | 1-Methyl-4-nitro-3-propylpyrazole-5-carboxamide
|
ITEMS |
SPECIFICATION |
|
CAS |
139756-01-7 |
|
MF |
C8H12N4O3 |
|
MW |
212.21 |
|
melting Point |
137.0 to 141.0 °C |
|
Density |
1.45±0.1 g/cm3(Predicted) |
|
Boiling point |
334.6±42.0 °C(Predicted) |
|
Refractive Index |
1.629 |
|
acidity coefficient(pKa) |
14.62±0.50(Predicted) |
Package and transportation of Introduction and application of CAS No.139756-01-7 | 1-Methyl-4-nitro-3-propylpyrazole-5-carboxamide
Package:0.1g,1g,5g,25g,100g,500g,1kg
Transportation: by courier/ by air/ by sea
Related Articles of CAS No.139756-01-7 | 1-Methyl-4-nitro-3-propylpyrazole-5-carboxamide
Separation and determination of synthetic impurities of sildenafil (Viagra) by reversed-phase high-performance liquid chromatography
V Nagaraju, D Sreenath, JT Rao, RN Rao - Analytical sciences, 2003 - jstage.jst.go.jp
… Its synthesis8 involves several steps, in which 4-amino 1-methyl-3-propylpyrazole-5carboxamide
(AMP) is initially obtained from 1-methyl-4-nitro3-propylpyrazole-5-carboxamide (MNC) …
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