Introduction and application of CAS No.481-74-3 | Chrysophanic acid
Chrysophanol has antibacterial, cough-relieving, and anti-aging effects.
Chrysophanic acid is a natural compound that has been shown to inhibit the activity of Cox-2 and COX-1, two enzymes involved in the inflammatory response. Chrysophanic acid also inhibits the production of prostaglandins, which are involved in pain and inflammation. The cytotoxicity of chrysophanic acid has been evaluated by testing its effect on HL-60 cells. This compound induces apoptosis in HL-60 cells by stimulating a calcium influx into the cytosol and changes in signal pathways that lead to mitochondrial membrane potential loss. Chrysophanic acid has been shown to be toxic to squamous carcinoma cell lines but not to normal human keratinocytes. It also inhibits the growth of cancerous cells at low doses but does not affect healthy cells.
Synonyms:
CHRYSOPHANICACID;CHRYSOPHANOL;
RHUBARBEXTRACT;1,8-dihydroxy-3-methyl-10-anthracenedione;
1,8-Dihydroxy-3-methyl-9,10-anthraquinone;
1,8-dihydroxy-3-methyl-anthraquinon;
2-Methyl-4,5-dihydroxyanthraquinone;
3-Methyl-1,8-dihydroxyanthraquinone
Specification of CAS No.481-74-3 | Chrysophanic acid
|
ITEMS |
SPECIFICATION |
|
CAS |
481-74-3 |
|
MF |
C15H10O4 |
|
MW |
254.24 |
|
Melting point |
194-198 °C |
|
Boiling point |
357.45°C (rough estimate) |
|
Density |
1.2693 (rough estimate) |
|
acidity coefficient(pKa) |
6.63±0.20(Predicted) |
Package and transportation of Introduction and application of CAS No.481-74-3 | Chrysophanic acid
Package:0.1g,1g,5g,25g,100g,500g,1kg
Transportation: by courier/ by air/ by sea

Related Articles of CAS No.481-74-3 | Chrysophanic acid
Chrysophanic acid shifts the differentiation tendency of BMSCs to prevent alcohol‐induced osteonecrosis of the femoral head
H Yu, P Liu, D Zhu, J Yin, Q Yang, Y Huang… - Cell …, 2020 - Wiley Online Library
… Chrysophanic acid (CPA) is a natural anthraquinone which has lipid regulation and bone
protection capacity. The aim of this study was to reveal the potential function of CPA and the …
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