CAS No.2378-95-2 | Diethyl N-[4-(methylamino)benzoyl]-L-glutamate

Introduction and application of CAS No.2378-95-2 | diethyl N-[4-(methylamino)benzoyl]-L-glutamate

diethyl N-[4-(methylamino)benzoyl]-L-glutamate is a prodrug that is metabolized to (S)-diethyl 2-(4-aminobenzamido)pentanedioate, which inhibits the enzyme dihydrofolate reductase. This prevents the synthesis of tetrahydrofolate, an essential cofactor in the synthesis of nucleic acids and amino acids. The antibiotic has been shown to be active against bacteria such as Mycobacterium tuberculosis and Staphylococcus aureus, but not against mammalian cells.

Synonyms:

(S)-Diethyl 2-(4-(methylamino)benzamido)pentanedioate;

diethyl (2S)-2-[[4-(methylamino)benzoyl]amino]pentanedioate;

N-(p-Methylaminobenzoyl)glutamic acid diethyl ester;

diethyl N-(p-methylaminobenzoyl)-L-glutamate;

(S)-Diethyl 2-(4-(methylamino)benzamido)pentanedioate;

P-N-Methylaminobenzoyl Glutamic Acid Diethyl Ester;

diethyl N-<4-(methylamino)benzoyl>AC1Q63IM;

Diethyl N-[4-(methylamino)benzoyl]-L-glutamate;

diethyl 4-(methylamino)benzoyl-L-glutamate;

diethyl p-methylaminobenzoyl-L-glutamate;

N-(4-Methylaminobenzoyl)-L-Glutamic Acid Diethyl ester;

Diethyl N-(p-N-methylaminobenzoyl)glutamate;

ethyl N-[p-(Methylamino)Benzoyl]-L-Glutamate;

diethyl <4-(N-methylamino)benzoyl>-L-glutamate;

Specification of CAS No.2378-95-2 | diethyl N-[4-(methylamino)benzoyl]-L-glutamate

Package and transportation of Introduction and application of CAS No.2378-95-2 | diethyl N-[4-(methylamino)benzoyl]-L-glutamate

Package:0.1g,1g,5g,25g,100g,500g,1kg

Transportation: by courier/ by air/ by sea

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[Synthesis of diethyl N-[p-(methylamino) benzoyl]-L-glutamate].

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… Using diethyl N-(p- aminobenzoyl)-L-glutamate (2) as a starting material via a one-pot process

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