Introduction and application of CAS No.1011-47-8 | 1-(Quinolin-2-yl)ethanone
1-(Quinolin-2-yl)ethanone is an inhibitor of proteolytic enzymes. It is a triazolopyrimidine that binds to the active site of proteases, thereby inhibiting their activity. 1-(Quinolin-2-yl)ethanone has been shown to be effective against viruses such as herpes simplex virus and Streptococcus faecalis, and bacterial infections such as streptococcus faecalis and Staphylococcus aureus.
1-(Quinolin-2-yl)ethanone also inhibits the production of matrix metalloproteinases, which play an important role in tumor development, by binding to the zinc ion in the enzyme's active site. This compound can also be used synergistically with copper chloride or hydrochloric acid to inhibit protease activity.
Synonyms:
1-quinolin-2-ylethanone;
1-(2-Quinolinyl)ethanone;
1-[2]Chinolyl-aethanon;
1-Quinolin-2-yl-ethanone;
methyl 2-quinolyl ketone;
2-Acetylquinoline;
Specification of CAS No.1011-47-8 | 1-(Quinolin-2-yl)ethanone
|
ITEMS |
SPECIFICATION |
|
CAS |
1011-47-8 |
|
MF |
C11H9NO |
|
MW |
171.2 |
|
Melting point |
52 °C |
|
Boiling point |
146-148 °C(Press: 13 Torr) |
|
Density |
1.154±0.06 g/cm3(Predicted) |
|
Storage |
2-8°C |
|
acidity coefficient(pKa) |
2.53±0.40(Predicted) |
Package and transportation of Introduction and application of CAS No.1011-47-8 | 1-(Quinolin-2-yl)ethanone
Package:0.1g,1g,5g,25g,100g,500g,1kg
Transportation: by courier/ by air/ by sea


Related Articles of CAS No.1011-47-8 | 1-(Quinolin-2-yl)ethanone
1-(Quinolin-2-yl) ethanone
RJ Butcher, JP Jasinski, AN Mayekar… - … Section E: Structure …, 2007 - scripts.iucr.org
The title compound, C11H9NO, crystallizes with four independent molecules in the asymmetric
unit. The formyl group in each molecule is coplanar with the attached quinoline ring …
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