Introduction and application of CAS 1353016-71-3 | DBCO-NHS Ester
DBCO-NHS ester is a cleavable ADC linker for the synthesis of antibody drug conjugates (ADCs).
Dbco- nhs ester is a synthetic substrate that is used for the preparation of proteins for use in diagnostic and analytical chemistry. This product can be used to determine the uptake of drugs and other substances by blood capillaries, as well as the activity of enzymes in cancer cells. Dbco- nhs ester is synthesized from 2,4-dinitrobenzene sulfonic acid (db) and bovine serum albumin (BSA).
It has been shown to bind to human serum albumin in an aqueous environment. This product can also be immobilized onto a solid support or used in vivo as a model protein. In addition, dbco-nhs ester may be used to study the immune functions of cells when they are cultured with this compound.
Synonyms:
Dibenzocyclooctyne-N-hydroxysuccinimidyl ester;
2,5-dioxopyrrolidin-1-yl 4-(didehydrodibenzo[b,f]azocin-5(6H)-yl)-4-oxobutanoate;
Dibenzylcyclooctyne-NHS ester;
DBCO-succinyl N-hydroxysuccinimidyl ester;
2,5-dioxopyrrolidin-1-yl 4-(11,12-didehydrodibenzo[b,f]azocin-5(6H)-yl)-4-oxobutanoate;
Specification of CAS 1353016-71-3 | DBCO-NHS Ester
|
ITEMS |
SPECIFICATION |
|
CAS |
1353016-71-3 |
|
MF |
C23H18N2O5 |
|
MW |
402.4 |
|
Density |
1.43±0.1 g/cm3(Predicted) |
|
Boiling point |
670.2±65.0 °C(Predicted) |
|
solubility |
Soluble in DMSO, DCM, DMF |
|
acidity coefficient(pKa) |
-0.23±0.20(Predicted) |
|
Stability |
Moisture Sensitive |
Package and transportation of Introduction and application of CAS 1353016-71-3 | DBCO-NHS Ester
Package:0.1g,1g,5g,25g,100g,500g,1kg
Transportation: by courier/ by air/ by sea
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