Products Description
Introduction and application of CAS：84313-38-2|FLUORESCEIN PHALLOIDIN
Fluorescein phalloidin is a fluorescently labeled toxin that binds specifically to F-actin, a major component of the cytoskeleton. This toxin has been widely used in scientific research to study the structure and function of the cytoskeleton, cell motility, and cell division.
Specification of CAS：84313-38-2|FLUORESCEIN PHALLOIDIN
Scientific research application
Fluorescein phalloidin has been widely used in scientific research to visualize the cytoskeleton in living and fixed cells. It can be used in combination with other fluorescent probes, such as antibodies or dyes, to label specific cellular structures and analyze their dynamics. Fluorescein phalloidin has been used to study the cytoskeleton in a variety of biological processes, such as cell migration, cell division, and cell signaling. It is also used to study the cytoskeleton in disease states, such as cancer and neurodegenerative diseases.
Mechanism
Fluorescein phalloidin specifically binds to F-actin, the filamentous form of actin that is a major component of the cytoskeleton. This binding is irreversible and results in stabilization of F-actin, preventing depolymerization. This results in the accumulation of F-actin in the cell, which can be observed by fluorescence microscopy. Fluorescein phalloidin has high affinity for F-actin with a dissociation constant (Kd) in the nanomolar range.
biochemical and physiological effects
Fluorescein phalloidin has been shown to have minimal biochemical and physiological effects on cells. It does not affect cell viability, proliferation or differentiation. However, it can affect the mechanical properties of cells by altering cytoskeletal structure and organization. This affects cell motility, adhesion and signaling.
Package of CAS：84313-38-2|FLUORESCEIN PHALLOIDIN
100g/drum
This product is valid for 24 months from the date of production when stored in a warm sealed state.
Safety and transportation
This product should be stored sealed at room temperature. Customers should carefully read the product treatment, material safety data sheet (MSDS) and labels before use, be familiar with the product's safety information, operating instructions, environmental impact, and wear appropriate personal protection as required. supplies.
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