Specification of CAS 857890-39-2 Lenvatinib mesylate
| Iteam | Specification |
| CAS | 857890-39-2 |
| Molecular Formula | C22H23ClN4O7S |
| Molecular Weight | 522.959 |
| Appearance | Solid |
| Synonyms | 4-(3-chloro-4-(cyclopropylaminocarbonyl)aminophenoxy)-7-methoxy-6-quinolinecarboxamide mesylate; Lenvatinib mesylate [USAN]; 4-(3-chloro-4-(cyclopropylaminocarbonyl)aminophenoxy)-7-methoxy-6-quinolinecarboxamide methanesulfonate; 4-[3-chloro-4-(cyclopropylcarbamoylamino)phenoxy]-7-methoxyquinoline-6-carboxamide,methanesulfonic acid; Lenvatinib mesilate (JAN); |
| Application | Lovatinib is a multi-target tyrosine kinase inhibitor, which may act on a variety of cancers, so Eisai is still studying Lovatinib for other cancers, such as hepatocellular carcinoma, non-small cell lung cancer, melanoma, breast cancer, lymphoma, ovarian cancer, etc. There were 62 clinical studies related to lovatib chemicalbookil. In July 2017, Eisai submitted a marketing application for levatinib as a first-line treatment for advanced hepatocellular carcinoma to the US FDA and the European Medicines Agency. In clinical trials, levatinib was superior to sorafenib, the current standard treatment for advanced hepatocellular carcinoma. |
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