Introduction of CAS:24979-70-2 | Poly(p-hydroxystyrene)
Phenol, 4-ethynyl- (also known as 4-ethynylphenol or 4-vinylphenol) is an important organic compound that has been studied extensively in recent years due to its wide range of applications in the field of science. It is a colorless, volatile liquid with a characteristic odor and is used in various industries, such as the pharmaceutical, food and cosmetic industries. In the scientific community, 4-ethynylphenol is used in research and development of new drugs and materials, as well as in the synthesis of various organic compounds.
Specification of CAS:24979-70-2 | Poly(p-hydroxystyrene)
|
ITEMS |
SPECIFICATION |
|
Flash point |
308°C |
|
Melt point |
360 °C (dec.) |
|
Density |
1.16 g/mL at 25 °C(lit.) |
|
Purity |
98% |
|
Refractive index |
n20/D 1.6 |
Research Application of CAS:24979-70-2 | Poly(p-hydroxystyrene)
Sensing and Detection Applications
Phenol, 4-ethynyl-, is also utilized in sensing and detection applications. A notable example is its use in Hg(II)-mediated intramolecular cyclization reaction in aqueous media, demonstrating its potential as a selective indicator for Hg(II) (Atta, Kim, Heo, & Cho, 2013). Furthermore, its incorporation in platinum(II) terpyridyl complexes with phenolic ethynyl ligands has been explored for sensing properties towards anions such as fluoride, acetate, and dihydrogenphosphate (Fan, Zhu, Dai, Zhang, & Chen, 2007).
Nanotechnology and Biomedical Engineering
In the field of nanotechnology and biomedical engineering, phenol, 4-ethynyl-, is pivotal in phenolic-enabled nanotechnology (PEN), particularly for biomedical applications. This includes biosensing, bioimaging, and disease treatment, highlighting its significant role in advancing medical technology and treatment strategies (Wu, Zhou, Creyer, Yim, Chen, Messersmith, & Jokerst, 2021).
Catalysis and Synthesis
Phenol, 4-ethynyl-, has been extensively studied in the context of catalysis and organic synthesis. For instance, it has been used in GaCl3-catalyzed ortho-ethynylation of phenols, a process that involves ethynylation at the ortho position with silylated chloroethyne (Kobayashi, Arisawa, & Yamaguchi, 2002). Additionally, phenol, 4-ethynyl-, has been a key component in the synthesis of acetylene-grafted resins derived from phenolics via azo coupling reactions, showcasing its versatility in creating novel resin materials with high ethynyl contents (Wang, Yang, Zhao, & Pei, 2008).


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