Introduction of CAS:2427-16-9 | 5-hydroxypentanenitrile
5-Hydroxypentanenitrile, also known as 5-HPN, is a chemical compound that has gained significant attention in the scientific community due to its potential applications in various fields. This compound is a colorless liquid that is soluble in water and has a faint odor. It has a molecular formula of C5H9NO, and its molecular weight is 99.13 g/mol.
Specification of CAS:2427-16-9 | 5-hydroxypentanenitrile
|
ITEMS |
SPECIFICATION |
|
Purity |
95% |
|
Boiling point |
77-78 °C(Press: 0.35 Torr) |
|
Density |
0.977 g/cm3(Temp: 25 °C) |
|
Acidity coefficient (pKa) |
14.95±0.10(Predicted) |
Research Application of CAS:2427-16-9 | 5-hydroxypentanenitrile
Synthesis of Diverse Chemical Compounds 5-Hydroxypent-2-enenitriles, related to 5-Hydroxypentanenitrile, are precursors to several classes of compounds with synthetic and biological interests. These compounds can be transformed into 5,6-dihydropyran-2-ones, 2,4-dienenitriles, or functionalized naphthalenes through various chemical reactions, showcasing their versatility in chemical synthesis (Zhang et al., 2013).
Enzymatic Synthesis of Pharmaceuticals The enzymatic synthesis of (R)-3-Hydroxypentanenitrile, a related compound, is significant in the production of immunosuppressive drugs. This process demonstrates the role of 5-Hydroxypentanenitrile derivatives in pharmaceutical manufacturing (Kawano et al., 2014).
Identification in Maillard Reaction 5-Hydroxy-3-mercapto-2-pentanone, a compound related to 5-Hydroxypentanenitrile, has been identified in the Maillard reaction, which is crucial in food chemistry for the development of flavors (Cerny & Guntz-Dubini, 2008).
Biosynthesis and Metabolic Engineering The metabolic engineering of microorganisms for the de novo production of 1,5-Pentanediol from glucose involves pathways that utilize 5-Hydroxypentanenitrile derivatives. This process is vital in creating sustainable methods for producing valuable chemicals from renewable resources (Cen et al., 2020).
Synthesis of Insect Hydrocarbons 5-Hydroxypentanenitrile derivatives are used in the synthesis of 1,5-dimethylalkanes, components of insect hydrocarbons. This application is significant in understanding and replicating natural insect products for various scientific purposes (Sonnet, 1976).



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