Introduction of CAS:2426-54-2 | 2-(Diethylamino)-ethyl acrylate
2-(Diethylamino)ethyl acrylate is a chemical compound that is related to acrylamide and methacrylate derivatives. It is known for its use in the synthesis of polymers with specific properties, such as thermosensitivity and pH-sensitivity. The compound is often used in the field of polymer chemistry and materials science, particularly in the development of smart materials and biosensors.
Chemical Reactions Analysis
The chemical reactivity of 2-(diethylamino)ethyl acrylate derivatives allows for their incorporation into various copolymers. In the study of the copolymer involving vinylferrocene and acrylamide, the presence of 2-(diethylamino)ethyl methacrylate facilitated the incorporation of vinylferrocene and affected the molecular weight of the resulting copolymer["]. Although not directly related to 2-(diethylamino)ethyl acrylate, the synthesis of γ-oxo-acrylates from ethyl 2,4-dioxoalkanoates demonstrates the reactivity of acrylate compounds in general.
Physical and Chemical Properties Analysis
Polymers containing 2-(diethylamino)ethyl acrylate units exhibit unique physical and chemical properties. For example, the copolymer synthesized in["] displayed reversible redox electrochemical characteristics due to the ferrocene moieties. This property was utilized in the development of electrochemical biosensors. Additionally, the thermosensitive and pH-sensitive nature of poly(N-[2-(diethylamino)ethyl]acrylamide) was observed, with phase separation temperatures in buffer solutions being influenced by concentration and pH.
Relevant Case Studies
The copolymer of vinylferrocene, acrylamide, and 2-(diethylamino)ethyl methacrylate was used to create biosensors that could measure glucose levels in blood. These biosensors showed good reproducibility and stability, with a low level of ferrocene leaching during testing["]. The study of poly(N-[2-(diethylamino)ethyl]acrylamide) in buffer solutions revealed its potential for applications that require responsiveness to environmental changes, such as smart drug delivery systems.
Specification of CAS:2426-54-2 | 2-(Diethylamino)-ethyl acrylate
|
ITEMS |
SPECIFICATION |
|
Refractive index |
n20/D 1.443(lit.) |
|
Boiling point |
199 °C(lit.) |
|
Density |
0.922 g/mL at 25 °C(lit.) |
|
Vapour pressure |
0.77 psi ( 20 °C) |
|
Flash point |
165 °F |
Research Application of CAS:2426-54-2 | 2-(Diethylamino)-ethyl acrylate
Surface Modification and Polymerization Techniques
Another application area is the modification of surface properties and polymerization techniques. Ding, Floyd, and Walters (2009) investigated the polymerization of poly(amino (meth)acrylate) brushes on silicon substrates, demonstrating successful surface-confined polymerization for a series of poly(amine (meth)acrylate) brushes (Ding, Floyd, & Walters, 2009).
Drug Delivery and Biomedical Applications
2-(Diethylamino)ethyl acrylate has also been employed in drug delivery and biomedical applications. For instance, Zhang et al. (2013) reported the use of 2-(diethylamino)ethyl acrylate-based thermoresponsive synthetic hydrogels for long-term human embryonic stem cell growth and pluripotency, offering a flexible and scalable approach for improving the efficacy and safety of human embryonic stem cell culture systems (Zhang et al., 2013). May-Pat, Cervantes-Uc, and Flores-Gallardo (2013) studied the fracture behavior of acrylic bone cements modified with 2-(diethylamino)ethyl-acrylate, highlighting its potential in biomedical material applications (May-Pat, Cervantes-Uc, & Flores-Gallardo, 2013).
Environmental and Polymer Science Applications
In the realm of environmental and polymer science, Jiang, Chun, Lu, and Xiaoyu (2017) synthesized dual-gas responsive polymers that display distinct CO2 and O2 responsiveness, indicating potential applications in biomedicine and environmental technology (Jiang, Chun, Lu, & Xiaoyu, 2017).


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