Introduction and application of CAS 1222-98-6 | 4-Nitrochalcone
4-Nitrochalcone is a natural compound that has been found to be effective in the treatment of leukemia. It is synthesized from 2-hydroxybenzoic acid and nitric acid. 4-Nitrochalcone reacts with maleic anhydride to form a mixture of 3,4-dihydroxybenzoic acid and 3,5-dihydroxybenzoic acid.
This reaction occurs in a reaction vessel at 220 degrees Celsius. The mixed product is then hydrolyzed by hydrochloric acid to release the 3,4-dihydroxybenzoic acid and 3,5-dihydroxybenzoic acid. The nitro group on the 3,5-dihydroxylbenzoic acid leaves as nitrous oxide gas during this process. The 3,5-dihydroxylbenzoic acids are potent inhibitors of mitochondrial membrane potential and can thus inhibit cell respiration.
Synonyms:
4-NITROBENZYLIDENEACETOPHENONE;
2-Propen-1-one, 3-(4-nitrophenyl)-1-phenyl-;
p-nitrobenzylideneacetophenone;4-Nitrochalcone 25GR;
4-nitro-chalcon;4-Nitrochalcone;2-(4-Nitrobenzylidene)acetophenone;
4'-nitrochalcone;4-Nitrostyrylphenyl ketone;4-nitrocalone;trans-4-Nitrochalcone;
Specification of CAS 1222-98-6 | 4-Nitrochalcone
|
ITEMS |
SPECIFICATION |
|
CAS |
1222-98-6 |
|
MF |
C15H11NO3 |
|
MW |
253.25 |
|
Melting point |
158-160 °C (lit.) |
|
Boiling point |
396.45°C (rough estimate) |
|
Density |
1.1934 (rough estimate) |
|
refractive index |
1.5500 (estimate) |
Package and transportation of Introduction and application of CAS 1222-98-6 | 4-Nitrochalcone
Package:0.1g,1g,5g,25g,100g,500g,1kg
Transportation: by courier/ by air/ by sea

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