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CAS:1222-98-6 | 4-Nitrochalcone

CAS:1222-98-6 | 4-Nitrochalcone

Name:4-Nitrochalcone
CAS:1222-98-6
MF:C5H8ClNO3
MW:253.25
Purity:97%
EINECS:214-949-5
Appearance:Light orange to Yellow to Green powder to crystal
Package: 5g,25g,100g,500g,1kg
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Product Introduction

Introduction and application of CAS 1222-98-6 | 4-Nitrochalcone

4-Nitrochalcone is a natural compound that has been found to be effective in the treatment of leukemia. It is synthesized from 2-hydroxybenzoic acid and nitric acid. 4-Nitrochalcone reacts with maleic anhydride to form a mixture of 3,4-dihydroxybenzoic acid and 3,5-dihydroxybenzoic acid.

 

This reaction occurs in a reaction vessel at 220 degrees Celsius. The mixed product is then hydrolyzed by hydrochloric acid to release the 3,4-dihydroxybenzoic acid and 3,5-dihydroxybenzoic acid. The nitro group on the 3,5-dihydroxylbenzoic acid leaves as nitrous oxide gas during this process. The 3,5-dihydroxylbenzoic acids are potent inhibitors of mitochondrial membrane potential and can thus inhibit cell respiration.

 

Synonyms:

4-NITROBENZYLIDENEACETOPHENONE;

2-Propen-1-one, 3-(4-nitrophenyl)-1-phenyl-;

p-nitrobenzylideneacetophenone;4-Nitrochalcone 25GR;

4-nitro-chalcon;4-Nitrochalcone;2-(4-Nitrobenzylidene)acetophenone;

4'-nitrochalcone;4-Nitrostyrylphenyl ketone;4-nitrocalone;trans-4-Nitrochalcone;

 

Specification of CAS 1222-98-6 | 4-Nitrochalcone

ITEMS

SPECIFICATION

CAS

1222-98-6

MF

C15H11NO3

MW

253.25

Melting point

158-160 °C (lit.)

Boiling point

396.45°C (rough estimate)

Density

1.1934 (rough estimate)

refractive index

1.5500 (estimate)

 

Package and transportation of Introduction and application of CAS 1222-98-6 | 4-Nitrochalcone

Package:0.1g,1g,5g,25g,100g,500g,1kg

Transportation: by courier/ by air/ by sea

 

product-763-725

 

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