Introduction and application of CAS No.83683-82-3 | 4-Nitro-1H-pyrrolo[2,3-b]pyridine
4-Nitro-1H-pyrrolo[2,3-b]pyridine is a deoxyribonucleoside that has been synthesized from chloride and its high yield can be attributed to the catalytic properties of the nitro group. The n-oxide form of 4-nitro-1H-pyrrolo[2,3-b]pyridine is an adenosine analogue with antiviral activity against HIV type 1 (HIV-1) and glycosylation. 4NPP has shown industrial potential as a medicament for the treatment of HIV infection. It is eliminated by hydrolysis in vivo to form 4-aminopyrrolo[2,3-b]pyridine.
Synonyms:
4-nitro-1H-pyrrolo<2,3-b>pyridine;
4-Nitro-7-azaindole;
1H-PYRROLO[2,3-B]PYRIDINE, 4-NITRO-;
Specification of CAS No.83683-82-3 | 4-Nitro-1H-pyrrolo[2,3-b]pyridine
|
ITEMS |
SPECIFICATION |
|
CAS |
83683-82-3 |
|
MF |
C7H5N3O2 |
|
MW |
163.13 |
|
Boiling point |
380.0±35.0 °C(Predicted) |
|
Density |
1.58 |
|
Refractive Index |
1.74 |
|
acidity coefficient(pKa)
|
2.28±0.20(Predicted) |
|
Storage |
Sealed in dry,Room Temperature |
Package and transportation of Introduction and application of CAS No.83683-82-3 | 4-Nitro-1H-pyrrolo[2,3-b]pyridine
Package:0.1g,1g,5g,25g,100g,500g,1kg
Transportation: by courier/ by air/ by sea


Related Articles of CAS No.83683-82-3 | 4-Nitro-1H-pyrrolo[2,3-b]pyridine
1,7‐Dideaza‐2′,3′‐dideoxyadenosine: Syntheses of Pyrrolo[2,3‐b]pyndine 2′,3′‐Dideoxyribofuranosides and Participation of Purine N(1) during HIV‐1 …
F Seela, R Gumbiowski - Helvetica chimica acta, 1991 - Wiley Online Library
… Compound 1 was also obtained from the direct glycosylation of 4‐nitro‐1H‐pyrrolo[2,3‐b]pyridine
(17) with the 2,3‐dideoxyribofuranosyl chloride 18. The triphosphate 25 of 1 showed …
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