CAS No.272-23-1 | Thieno[2,3-b]pyridine

Introduction and application of CAS No.272-23-1 | Thieno[2,3-b]pyridine

Thieno[2,3-b]pyridine is a quinoline derivative that has been shown to be a potent antitumor agent. It inhibits the growth of human liver cancer cells and human breast cancer cells. Thieno[2,3-b]pyridine binds to the Pim-1 protein, which regulates cell proliferation. This interaction blocks the activation of cyclin D1 and inhibits the production of downstream proteins such as c-Myc, p27kip1, and cyclin E. Thieno[2,3-b]pyridine also inhibits the activity of DNA topoisomerase I by binding to its active site. The inhibition leads to accumulation of DNA breaks in tumor cells that are not repaired by this enzyme.

Synonyms:

Thieno[2,3-b]pyridine (8CI,9CI);

Specification of CAS No.272-23-1 | Thieno[2,3-b]pyridine

Package and transportation of Introduction and application of CAS No.272-23-1 | Thieno[2,3-b]pyridine

Package:0.1g,1g,5g,25g,100g,500g,1kg

Transportation: by courier/ by air/ by sea

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