Introduction and application of CAS No.231278-84-5 | 5-(4-((3-Chloro-4-((3-fluorobenzyl)oxy)phenyl)amino) quinazolin-6-yl)furan-2-carbaldehyde
5-(4-((3-Chloro-4-((3-fluorobenzyl)oxy)phenyl)amino)quinazolin-6-yl)furan-2-carbaldehyde is a heterocyclic compound that has been used to study protein tyrosine kinase activity. This drug binds to the active site of the enzyme and inhibits its function by forming an irreversible covalent bond with the enzyme's reactive cysteine residue, which prevents the transfer of phosphate groups from ATP to the substrate (tyrosine).
Lapatinib intermediate.
Synonyms:
CTK1A1282;
5-[4-[3-Chloro-4-(3-fluorobenzyloxy)anilino]-6-quinazolinyl]furan-2-carboxaldehyde;
5-(4-(4-(3-fluorobenzyloxy)-3-chlorophenylamino)quinazolin-6-yl)furan-2-carbaldehyde;
5-(4-[3-chloro-4-(3-fluorobenzyloxy)-anilino]-6-quinazolinyl)-furan-2-carbaldehyde;
5-{4-[3-chloro-4-(3-fluorobenzyloxyl)-phenylamino]-quinazolin-6-yl}-furan-2-carbaldehyde;
AGN-PC-0D1ZTN;
5-(4-{3-chloro-4-[(3-fluorobenzyl)oxy]anilino}-6-quinazolinyl)-2-furaldehyde;
5-(4-((3-Chloro-4-((3-fluorobenzyl)oxy)phenyl)amino)quinazolin-6-yl)furan-2-carbaldehyde;
5-(4-((3-chloro-4-((3-fluorobenzyl)oxy)phenyl)amino)quinazolin-6-yl)-2-furaldehyde;
Specification of CAS No.231278-84-5 | 5-(4-((3-Chloro-4-((3-fluorobenzyl)oxy)phenyl)amino) quinazolin-6-yl)furan-2-carbaldehyde
|
ITEMS |
SPECIFICATION |
|
CAS |
231278-84-5 |
|
MF |
C26H17ClFN3O3 |
|
MW |
473.88 |
|
Density |
1.407±0.06 g/cm3(Predicted) |
|
Boiling point |
650.3±55.0 °C(Predicted) |
|
Melting point |
227.0 to 231.0 °C |
|
acidity coefficient(pKa) |
5.18±0.30(Predicted) |
|
Solubility |
DMSO (Slightly), Methanol (Very Slightly) |
Package and transportation of Introduction and application of CAS No.231278-84-5 | 5-(4-((3-Chloro-4-((3-fluorobenzyl)oxy)phenyl)amino) quinazolin-6-yl)furan-2-carbaldehyde
Package:0.1g,1g,5g,25g,100g,500g,1kg
Transportation: by courier/ by air/ by sea
Related Articles of CAS No.231278-84-5 | 5-(4-((3-Chloro-4-((3-fluorobenzyl)oxy)phenyl)amino) quinazolin-6-yl)furan-2-carbaldehyde
FDA approved six-membered ring fused pyrimidine-based derivatives
S Arora, R Kumar - Fused Pyrimidine-Based Drug Discovery, 2023 - Elsevier
… Cyclic acetal of 8.1.173 was cleaved under the acidic condition to obtain 5-(4-((3-chloro-4-((3-fluorobenzyl)oxy)phenyl)amino)quinazolin-6-yl)furan-2-carbaldehyde
Hot Tags: cas no.231278-84-5 | 5-(4-((3-chloro-4-((3-fluorobenzyl)oxy)phenyl)amino) quinazolin-6-yl)furan-2-carbaldehyde, China cas no.231278-84-5 | 5-(4-((3-chloro-4-((3-fluorobenzyl)oxy)phenyl)amino) quinazolin-6-yl)furan-2-carbaldehyde manufacturers, factory, 4 Amino 4H 1 2 4 triazole, Methyl toluenesulfonate, 2-Bromo-m-xylene, Pharmaceutical Intermediates, Cellulose Acetate Butyrate, 3 deoxy adenosin
