Introduction and application of CAS No.112888-43-4 | 6-(Bromomethyl)-2-methyl-4(3H)-quinazolinone
Raltitrexed intermediate.
6-(Bromomethyl)-2-methyl-4(3H)-quinazolinone (6BMQ) is a synthetic molecule that has been designed to mimic the pharmacophores of quinazoline drugs. This compound is hydrolyzed by alkaline hydrolysis and acetylated in acidic conditions. 6BMQ binds to DNA and inhibits DNA synthesis, leading to cell death.
It also has anti-cancer activity, which may be due to its ability to hybridize with DNA. 6BMQ is also a chalcone derivative with an acidic hydrolysis product.
Synonyms:
6-(Bromomethyl)-2-methyl-4(3H)-quinazolinone;
6-(bromomethyl)-2-methyl-1H-quinazolin-4-one;
6-(Bromomethyl)-2-methylquinazolin-4(3H)-one;
Specification of CAS No.112888-43-4 | 6-(Bromomethyl)-2-methyl-4(3H)-quinazolinone
|
ITEMS |
SPECIFICATION |
|
CAS |
112888-43-4 |
|
MF |
C10H9BrN2O |
|
MW |
253.1 |
|
Boiling Point |
399.4ºC at 760mmHg |
|
Density |
1.63g/cm3 |
|
Flash Point |
195.3ºC |
|
Refractive Index |
1.669 |
|
Vapor Pressure |
1.37E-06mmHg at 25°C |
Package and transportation of Introduction and application of CAS No.112888-43-4 | 6-(Bromomethyl)-2-methyl-4(3H)-quinazolinone
Package:0.1g,1g,5g,25g,100g,500g,1kg
Transportation: by courier/ by air/ by sea


Related Articles of CAS No.112888-43-4 | 6-(Bromomethyl)-2-methyl-4(3H)-quinazolinone
Synthesis and in vitro antitumor activity of 4 (3H)-quinazolinone derivatives with dithiocarbamate side chains
SL Cao, YP Feng, YY Jiang, SY Liu, GY Ding… - Bioorganic & medicinal …, 2005 - Elsevier
… ,6-dimethyl-4(3H)-quinazolinone (5), which was converted to 6-bromomethyl-2-methyl-4(3H)-quinazolinone
(6… by the reaction of 6-bromomethyl-2-methyl-4(3H)-quinazolinone with CS 2 …
Hot Tags: cas no.112888-43-4 | 6-(bromomethyl)-2-methyl-4(3h)-quinazolinone, China cas no.112888-43-4 | 6-(bromomethyl)-2-methyl-4(3h)-quinazolinone manufacturers, factory, Cordycepin, Cellulose Acetate Butyrate, 4 Amino 4H 1 2 4 triazole, Pharmaceutical Intermediates, 3 deoxy adenosin, Methyl toluenesulfonate









![CAS: 66104-81-2 | N-[4-(Methylamino)benzoyl]-L-glutamic Acid Zinc Salt](/uploads/202340266/small/cas-66104-81-2-n-4-methylamino-benzoyl-l5c31c542-9f2b-481b-ac54-3643be247c1a.png?size=195x0)


