CAS 91-00-9 | Benzhydrylamine | Pharmaceutical Intermediate & Chiral Resolution Reagent | China Manufacturer
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01 PURITY ≥97% GC purity |
02 BOILING POINT 295 °C High-purity distillation |
03 REFRACTIVE INDEX n20/D 1.595 Liquid product |
04 PACKAGING 1 kg – 200 kg Bulk available |
Packaging: 1 kg – 200 kg | Lead Time: 3–7 days | Origin: Made in China
Documentation: COA & SDS provided | Samples: Research samples available
KEY APPLICATIONS
API Intermediate / Chiral Resolution / Organic Synthesis Block
Benzhydrylamine (CAS 91-00-9) - Product Overview
As a China-based manufacturer, Alfa Chemical supplies Benzhydrylamine (CAS 91-00-9) from Zhengzhou. It is a clear colorless to yellow liquid with a characteristic amine odor and mild alkalinity. The compound is a versatile pharmaceutical intermediate and a useful chiral resolution reagent.
Benzhydrylamine is supplied at ≥97% purity (GC). It has a boiling point of 295 °C, a refractive index of n20/D 1.595, and a density of 1.063 g/mL at 25 °C. The material is miscible with chloroform, dimethylsulfoxide, and methanol, and slightly miscible with water. Store under inert gas (nitrogen or argon) at 2–8 °C.
Typical applications include API synthesis, chiral resolution, and use as a building block for organic functional molecules and bioactive compounds. It is also used in the preparation of furan-2-carboxylic acid benzhydrylamide by reaction with furan-2-carbonyl chloride. Related pharmaceutical intermediates are also available.
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Key Features of Benzhydrylamine
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01 |
High purity Supplied at ≥97% (GC). Each lot is tested by gas chromatography and titration before release. |
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02 |
Chiral resolution Widely used as a resolving agent for chiral acids and as a building block in asymmetric synthesis. Forms diastereomeric salts that can be separated by crystallization. |
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Liquid handling Room-temperature liquid (mp 12 °C) - easy to transfer, dilute, and dose without melting or dissolution steps. |
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Documentation Batch-specific COA and GHS-format SDS provided with every shipment. |
Applications: Pharmaceutical Intermediate & Chiral Resolution
01. API Intermediate
Challenge: Pharmaceutical synthesis requires a reliable building block for introducing the benzhydryl group into active pharmaceutical ingredients.
Solution: Benzhydrylamine serves as a key intermediate in pharmaceutical synthesis, particularly for the development of antihistamines and antidepressants.
Result: Efficient introduction of the benzhydryl scaffold into target APIs with consistent batch quality.
Request technical data →02. Chiral Resolution
Challenge: Separating enantiomers from racemic mixtures is a critical and often costly step in pharmaceutical production.
Solution: Benzhydrylamine forms diastereomeric salts with racemic carboxylic acids, enabling enantiomer separation by crystallization. It is widely used for resolving mandelic acid and 2-chloromandelic acid derivatives.
Result: High enantiomeric purity (>96% ee) with straightforward recovery of the resolving agent.
Ask about resolution protocols →03. Organic Synthesis Building Block
Challenge: Synthetic chemists need a versatile amine building block for structural modification and preparation of functional molecules.
Solution: Benzhydrylamine is used for amide formation, reductive amination, and N-alkylation. It reacts with furan-2-carbonyl chloride to form furan-2-carboxylic acid benzhydrylamide.
Result: Access to a wide range of benzhydryl-functionalized intermediates for pharmaceutical and agrochemical research.
Request a sample →Benzhydrylamine Specifications
Detailed specifications for CAS 91-00-9 Benzhydrylamine are listed below. For batch-specific COA or SDS, please contact us.
| Item | Specification |
|---|---|
| Product Name | Benzhydrylamine |
| Synonym | Aminodiphenylmethane; α-Phenylbenzylamine; 1,1-Diphenylmethylamine |
| CAS Number | 91-00-9 |
| EINECS | 202-032-2 |
| Molecular Formula | C13H13N |
| Molecular Weight | 183.25 g/mol |
| Purity | ≥97% (GC) |
| Appearance | Clear colorless to yellow liquid |
| Melting Point | 12 °C |
| Boiling Point | 295 °C |
| Flash Point | >230 °F (110 °C) |
| Density | 1.063 g/mL at 25 °C |
| Refractive Index | n20/D 1.595 |
| pKa | 8.41 ± 0.10 (predicted) |
| Solubility | Miscible with chloroform, DMSO, methanol. Slightly miscible with water. |
| Storage | 2–8 °C under inert gas (nitrogen or argon) |
| Packaging | 1 kg / 5 kg / 25 kg / 200 kg |
| Documents | COA, SDS |
Every shipment includes COA and SDS. Click below to request batch-specific documents or technical data for CAS 91-00-9:
Quality Control for Chiral Resolution Reagent
Each batch is tested for purity (GC), appearance, refractive index, and water content before release. The COA you receive matches the lot number on the label.
We are based in Zhengzhou, China. If your project needs a custom specification - different purity grade, larger pack size, or a third-party test - contact us before you order.
Packaging & Shipping from China Manufacturer
Standard packaging: 1 kg, 5 kg, 25 kg, and 200 kg. Custom pack sizes available for bulk orders. The product is a liquid and should be stored at 2–8 °C under inert gas before dispatch.
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Shipped worldwide from China by courier, air, or sea. For special packaging or urgent requests, contact us directly.
Why Buy Benzhydrylamine from Alfa Chemical
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Stock |
Held in Zhengzhou. 1 kg to 200 kg ship same week; bulk orders ship in 2–3 weeks. |
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Documentation |
Batch-specific COA with every lot. Third-party testing can be arranged before shipment on request. |
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Experience |
Supplying pharmaceutical and research groups since 2018. If you are new to chiral resolution, ask us - we will tell you what usually goes wrong. |
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Shipping |
Courier or air freight, worldwide from China. Non-hazardous for transport in most jurisdictions. |
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Customization |
If the ≥97% grade does not fit your process, tell us the purity or pack size you need. We can quote custom specifications. |
Browse other pharmaceutical intermediates or send us your spec.
Frequently Asked Questions
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Q1. What purity grades are available? We supply ≥97% (GC) as standard. Higher purity grades and custom specifications can be quoted on request. Q2. How should I store Benzhydrylamine? Store at 2–8 °C under inert gas (nitrogen or argon). Keep the container tightly sealed and protected from moisture and air. Q3. What is the typical lead time? 3–7 days for stock items. Bulk orders and custom specifications may require additional time. Contact us for current availability. |
Q4. Do you provide COA and SDS? Yes, every lot. The COA lists purity, appearance, refractive index, and water content. The SDS is in GHS format. Ask us for the lot number. Q5. Can I get a smaller sample first? Yes. We stock 1 kg and 5 kg packs for evaluation. Tell us what you are testing and we will match the pack size to your experiment. Q6. Is this product suitable for chiral resolution? Yes. Benzhydrylamine is widely used as a chiral resolving agent for racemic acids. It forms diastereomeric salts that can be separated by crystallization. |
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About Alfa Chemical: Based in Zhengzhou, China, Alfa Chemical supplies fine chemicals, biochemicals, and specialty intermediates to research and industrial customers worldwide.
Disclaimer: This product is intended for research and industrial use only. Not for food, pharmaceutical, or cosmetic applications without specific regulatory compliance testing. All specifications are typical values and should be confirmed against the batch-specific Certificate of Analysis before use.
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