Specification of CAS 608-66-2 Galactitol
| Iteam | Specification |
| CAS | 608-66-2 |
| English Name | Dulcitol |
| Description | Galactitol (dulcitol) is a sugar alcohol, the reduction product of galactose. In people with galactokinase deficiency, a form of galactosemia, excess dulcitol forms in the lens of the eye leading to cataracts. Galactitol is produced from galactose in a reaction catalyzed by aldose reductase. Galactose itself comes from the metabolism of the disaccharide lactose into glucose and galactose. The other common galactose metabolism defect is a defect in galactose-1-phosphate uridylyltransferase, an autosomal recessive disorder, which also causes a buildup of galactitol as a result of increased concentrations of galactose-1-phosphate and galactose. The toxicity associated with galactose-1-phosphate uridylyltransferase deficiency is associated with symptoms of hepatosplenomegaly and mental retardation in addition to the cataracts caused by galactitol buildup. |
| Molecular Formula | C6H14O6 |
| Molecular Weight | 182.17 |
| Density | 1.28 g/mL at 25ºC |
| Boling Point | 275-280ºC (1 mmHg) |
| Melting Point | 188-189ºC |
| Storage Condition | liquid |
| Synonyms | Schleimsaure; Galactitol; Dulcite; (2R,3S,4R,5S)-hexane-1,2,3,4,5,6-hexaol; dulcitol; D-galactitol; |
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