Introduction and application of CAS 1310726-60-3 | Upadacitinib
Inhibitor of Janus kinase JAK-1
Scientific research reagents are widely used in molecular biology, pharmacology and other scientific research, and are strictly prohibited from use on the human body. Upadacitinib (ABT-494) is a highly effective and selective JAK1 inhibitor used in the treatment of some autoimmune diseases and research in related fields.
Synonyms:
(3S,4R)-3-Ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)-1-pyrrolidinecarboxamide;
ABT 494;
Upadacitinib;
1-Pyrrolidinecarboxamide, 3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)-, (3S,4R)-;
rel-(-)-(3S,4R)-3-Ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide;
Specification of CAS 1310726-60-3 | Upadacitinib
|
ITEMS |
SPECIFICATION |
|
CAS |
1310726-60-3 |
|
MF |
C17H19F3N6O |
|
MW |
380.37 |
|
Density |
1.56±0.1 g/cm3(Predicted) |
|
EINECS |
213-161-9 |
|
acidity coefficient (pKa) |
11.89±0.60(Predicted) |
Package and transportation of Introduction and application of CAS 1310726-60-3 | Upadacitinib
Package:0.1g,1g,5g,25g,100g,500g,1kg
Transportation: by courier/ by air/ by sea


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Upadacitinib for the treatment of rheumatoid arthritis
L Serhal, CJ Edwards - Expert Review of Clinical Immunology, 2019 - Taylor & Francis
… upadacitinib extended-release 15 and 30 mg daily selected in phase III RA studies have shown
a near-maximum efficacy in phase II studies. Upadacitinib … ), upadacitinib was superior to …
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