Introduction and application of CAS No.78919-26-3 | isoursodeoxycholic acid
isoursodeoxycholic acid is a bile acid that is synthesized in the liver and secreted into the intestine. It is used as a treatment for congestive heart failure, HIV infection, bowel disease, and autoimmune diseases. isoursodeoxycholic acid has been shown to be a potent inhibitor of hydroxylation of cholesterol in the liver. It also exhibits an ability to increase the transport rate of cholesterol from the liver to other tissues in the body.
isoursodeoxycholic acid inhibits monoethyl ether formation by competing with ethylene oxide for binding sites on microsomal proteins. This compound also protects against primary sclerosing cholangitis and ursodiol therapy by preventing enzymatic inactivation of bile acids.
It is used as an anticholelithogenic.
Synonyms:
3beta-Ursodeoxycholic acid;
(3β,5β,7β)-3,7-Dihydroxycholan-24-oic acid;
Chenodiol Chenodesoxycholic acid;
sodium sat of chenodeoxycholic acid;
chenodesoxycholate de sodium;
Chenodeoxycholate sodium salt;
Chenodeoxycholic Saeure;
sodium chenodexoycholate;
cenodeoxycholate;
sodiumchenodesoxycholate;
sodium chenodeoxycholate;
chenodeoxycholic acid sodium salt;
Specification of CAS No.78919-26-3 | isoursodeoxycholic acid
|
ITEMS |
SPECIFICATION |
|
CAS |
78919-26-3 |
|
MF |
C24H40O4 |
|
MW |
392.57 |
|
Melting point |
184 - 186°C |
|
Density |
1.128±0.06 g/cm3(Predicted) |
|
Boiling point |
547.1±25.0 °C(Predicted) |
|
acidity coefficient(pKa) |
4.76±0.10(Predicted) |
Package and transportation of Introduction and application of CAS No.78919-26-3 | isoursodeoxycholic acid
Package:0.1g,1g,5g,25g,100g,500g,1kg
Transportation: by courier/ by air/ by sea
Related Articles of CAS No.78919-26-3 | isoursodeoxycholic acid
Formation of iso-ursodeoxycholic acid during administration of ursodeoxycholic acid in man
U Beuers, S Fischer, U Spengler, G Paumgartner - Journal of hepatology, 1991 - Elsevier
The appearance of iso-ursodeoxycholic acid (isoUDCA; 3β,7β-dihydroxy-5β-cholan-24-oic
acid) in serum of patients with chronic cholestatic liver disease and of healthy subjects during …
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