Introduction and application of CAS: 66-27-3 | Methyl methanesulfonate
Sulfonate substances such as methanesulfonic acid and benzenesulfonic acid react with trace amounts of lower alcohols to generate alkyl sulfonate esters, such as methyl methanesulfonate (MMS), ethyl methanesulfonate (EMS), isopropyl methyl methanesulfonate (IMS), n-butyl methanesulfonate (NBMS), and aryl sulfonate esters such as methyl benzenesulfonate (MBS), ethyl benzenesulfonate (EChemicalbookBS), p-toluenesulfonate (MP) -TS), these substances can alkylate with DNA, which may become a cause of cancer. Therefore, it is very important to control the Threshold of Toxicological Concern (TTC) level of such impurities in drugs. The European EMA has issued a report on genotoxic impurities. The maximum intake is 1.5μg/d.
Specification of CAS: 66-27-3 | Methyl methanesulfonate
|
ITEMS |
SPECIFICATION |
|
CAS |
456-48-4 |
| MF | C7H5FO |
|
MW |
124.11 |
|
Melting point |
173 C |
|
Appearance |
Colorless Liquid |
|
Purity |
99% |
|
Flash point |
134 °F |
|
Storage condition |
2-8°C |
| Production | China |
Package and transportation of CAS: 66-27-3 | Methyl methanesulfonate
Package:10g, 100g, 1kg 25kg 1000kg
Transportation: by courier/ by air/ by sea
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