Products Description
Introduction and application of CAS:1603-91-4| 2-Amino-4-methylthiazole
Used in organic synthesis. Usage: Used as a pharmaceutical intermediate. The production method is derived from the action of chloroacetone and thiourea. Add water and thiourea to the reactor, stir, and add chloroacetone dropwise within half an hour. As the reaction proceeds, thiourea gradually dissolves. Reflux the reaction for 2 hours, then add granular sodium hydroxide while cooling and slowly stirring. Then separate the upper oil, extract the aqueous layer with ether, combine the dark red oil with the extract, dry with sodium hydroxide, and filter. After evaporating the ether from the filtrate, the residue is distilled under reduced pressure, and the 117-120°C (1.07kPa) or 130-133°C (2.40kPa) fraction is collected to obtain the product, with a yield of 70-75%.
Specification of CAS:1603-91-4| 2-Amino-4-methylthiazole
Melting point 44-47°C(lit.)
Boiling point 231-232°C (lit.)
Density 1.176(estimate)
Refractive index 1.5000(estimate)
Flash point >230°F
Storage conditionsKeepindarkplace,Sealedindry,RoomTemperature
Solubility in methanol
form solid
Acidity coefficient (pKa)5.36±0.10(Predicted)
Color white to yellow to green
Package of CAS:1603-91-4| 2-Amino-4-methylthiazole
100G/1kg/25kg drum
This product is valid for 24 months from the production date when stored in a warm sealed state.
Safety and Transportation
This product should be stored and sealed at room temperature. Customers should carefully read the product treatment, material safety data sheet (MSDS), and labels before use, be familiar with the product's safety information, operating instructions, and environmental impact, and wear appropriate personal protection as required. supplies.
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