Introduction of CAS:105-62-4 | PROPYLENE GLYCOL DIOLEATE
Propylene glycol dioleate (PGDO) is a synthetic compound that is widely used in the field of science and research. It is commonly used as a surfactant, emulsifier, and solubilizer in various applications. PGDO is a liquid that is soluble in water and has a low toxicity level.
Specification of CAS:105-62-4 | PROPYLENE GLYCOL DIOLEATE
|
ITEMS |
SPECIFICATION |
|
Color |
Light yellow |
|
Purity |
96% |
|
Boiling point |
641.2±48.0 °C(Predicted) |
|
Form |
liquid |
Research Application of CAS:105-62-4 | PROPYLENE GLYCOL DIOLEATE
Target of Action
Propylene glycol dioleate is a monoester of propylene glycol and oleic acid . It is primarily used in the formulation of cosmetics and personal care products, including moisturizers, cleansing products, fragrance products, and makeup products such as foundations and lipsticks . Its primary targets are the skin and hair, where it acts as a conditioning agent, emollient, and surfactant .
Mode of Action
As an emollient, this compound softens and soothes the skin by forming an oily layer on the skin's surface, which helps to reduce water loss and keep the skin hydrated . As a surfactant, it helps to reduce the surface tension of substances, allowing them to spread more easily . This property is particularly useful in cosmetic formulations, where it helps to distribute the product evenly on the skin or hair .
Biochemical Pathways
This compound is typically produced from the reaction of propylene glycol with oleic acid . The biochemical pathways involved in the production of propylene glycol, also known as 1,2-propanediol, can be harnessed into fermentation processes to produce this compound . .
Pharmacokinetics
The pharmacokinetics of propylene glycol, a component of this compound, has been studied. It is rapidly absorbed and has a terminal elimination half-life of approximately 4 hours . The average apparent total body clearance is around 0.1 L kg/h and may be concentration-dependent . The apparent volume of distribution approximates total body water . .
Result of Action
The primary result of the action of this compound is the conditioning and moisturizing of the skin and hair . By forming an oily layer on the skin's surface, it helps to prevent water loss and keep the skin hydrated . In hair care products, it helps to improve hair texture and manageability .



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