Introduction of CAS:38594-42-2 | 2,3-DICHLOROBENZYL ALCOHOL
The synthesis of derivatives related to 2,3-dichlorobenzyl alcohol involves various methods. For instance, a practical and safe synthesis of 1,2-bis(trimethylsilyl)benzene from 1,2-dichlorobenzene has been achieved using a hybrid metal of Mg and CuCl in the presence of LiCl . Another study reports the synthesis of 2-(2,4-Dichlorobenzylidene)-2,3-dihydroinden-1-one under solvent-free conditions, which is environmentally friendly and uses readily available raw materials . Additionally, the development of α-(Chloromethyl)-2,4-dichlorobenzyl alcohol as an important intermediate in China has been reviewed, with future research likely focusing on mesoporous molecular sieve supported metal oxides and chiral ligands.
The molecular structure of 2,3-dichlorobenzyl alcohol-related compounds has been studied using various techniques. For example, the structure of 2,3-Dichloro-3',4'-dihydroxybiphenyl, a metabolite of 2,3-dichlorobiphenyl, displays intramolecular O-H···O hydrogen bonding and π-π stacking between chlorinated benzene rings . The structural, wave functional, and electronic properties of a related compound, 3-{(E)-[(3,4-dichlorophenyl)imino]methyl}benzene-1,2-diol, have been investigated using density functional theory, revealing insights into its optimized geometrical properties and electronic states.
Specification of CAS:38594-42-2 | 2,3-DICHLOROBENZYL ALCOHOL
|
ITEMS |
SPECIFICATION |
|
Melt point |
85-88 °C(lit.) |
|
Boiling point |
271.2±25.0 °C(Predicted) |
|
Density |
1.392±0.06 g/cm3(Predicted) |
|
Form |
powder to crystal |
|
Color |
White to Almost white |
Research Application of CAS:38594-42-2 | 2,3-DICHLOROBENZYL ALCOHOL
Synthesis and Chemical Properties
2,3-Dichlorobenzyl alcohol is an important chemical intermediate with a wide range of applications. Li Ga (2014) explored the synthesis of α-(Chloromethyl)-2,4-dichlorobenzyl alcohol, emphasizing its significance in chemical research and industrial applications. The study highlighted future research directions focusing on mesoporous molecular sieves and metal oxides as key components (Li Ga, 2014). Additionally, Sundaraganesan et al. (2006) conducted detailed Fourier transform Raman and infrared spectroscopic studies of 3,4-dichlorobenzyl alcohol, contributing to a deeper understanding of its molecular structure and characteristics (Sundaraganesan et al., 2006).
Antibacterial and Antifungal Properties
Research has also been conducted on the antibacterial and antifungal properties of substituted benzyl alcohols, including 2,4-dichlorobenzyl alcohol. Carter et al. (1958) found that 2,4-dichlorobenzyl alcohol demonstrated significant bactericidal activity, highlighting its potential use in microbial control (Carter et al., 1958).
Crystal Structure Analysis
The crystal structure of 2,4-dichlorobenzyl alcohol has been analyzed to understand its antimicrobial properties and pharmaceutical applications. Bambagiotti-Alberti et al. (2007) investigated its crystallization and molecular packing, revealing insights into its structural properties (Bambagiotti-Alberti et al., 2007).
Industrial and Laboratory Applications
Further studies have focused on the optimization of synthesis techniques and potential industrial applications. For example, Gan (2011) optimized the synthesis technology of α-(chloromethyl)-2,4-dichlorobenzyl alcohol, an antifungal agent, making the process more suitable for industrial applications (Gan, 2011). Another study by Ishikawa and Manabe (2008) examined the ortho-selective cross-coupling of dihalobenzenes, including dichlorobenzyl alcohols, in the presence of palladium-based catalysts, demonstrating its relevance in chemical synthesis (Ishikawa & Manabe, 2008).
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