Specification of CAS CAS 35109-88-7 | 2-IODOADENOSINE
| Iteam | Specification |
| CAS | 35109-88-7 |
| Description | An intermediate in the synthesis of isoguanosine (crotonoside or 2-hydroxyadenosine), a naturally occuring nucleoside analogue of guanosine. Isoguanosine is incorporated into mammalian but not bacterial nucleic acids, stimulates the accumulation of cyclic AMP in the brain, and is an inhibitor of IMP:pyrophosphorylase. |
| English Name | (2R,3R,4S,5R)-2-(6-amino-2-iodopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol |
| Molecular Formula | C10H12IN5O4 |
| Molecular Weight | 393.138 |
| Boiling Point | 776.3ºC at 760 mmHg |
| Density | 2.69 g/cm3 |
| Flash Point | 423.3ºC |
| Melting Point | 200ºC (dec.) |
| Appearance | Off-white crystalline solid |
| Synonyms | 2-IODOADENOSINE; 2-iodo-2',3'-O-isopropylidene-adenosine; Adenosine,2-iodo; 2-idodadenosine; 6-Amino-2-iodo-9-(β-D-ribofuranosyl)purine; 2-Iodo-D-adenosine; |
| Application | 2-adenosine iodide is an intermediate in the synthesis of isoguanosine (crotonoside or 2-hydroxy-adenosine), which is the natural nucleoside analogue of guanosine. Isoguanosine is incorporated into mammalian rather than bacterial nucleic acids, stimulates the accumulation of cyclic adenosine (AMP) in the brain, and is an inhibitor of the pyrophosphorylase IMP. |
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