CAS:2357-52-0 | 4-Bromo-2-fluoroanisole

Introduction of CAS:2357-52-0 | 4-Bromo-2-fluoroanisole

4-Bromo-2-fluoroanisole (4-Br-2-FA) is an organic compound belonging to the class of aromatic ethers, and is a key starting material in the synthesis of a variety of organic compounds. It is a colorless liquid with a boiling point of 101-102 °C, and is soluble in most organic solvents. 4-Br-2-FA is a versatile intermediate used in the synthesis of a variety of organic compounds, including pharmaceuticals, agrochemicals, dyes, and fragrances. It has been used in the synthesis of several new pharmaceuticals, including a new class of antifungal agents, and has also been used in the synthesis of a variety of other compounds.

Specification of CAS:2357-52-0 | 4-Bromo-2-fluoroanisole

Research Application of CAS:2357-52-0 | 4-Bromo-2-fluoroanisole

4-Bromo-2-fluoroanisole plays a significant role in synthesizing black fluorane dye, an essential component in thermal papers. This dye, specifically 2-anilino-3-methyl-6-dibutylaminofluorane (ODB-2), is a key material in creating heat and pressure-sensitive dyes. A study by Xie et al. (2020) developed a continuous homogeneous bromination technology in a modular microreaction system, which improved the process of synthesizing 4-bromo-3-methylanisole, a related compound, with high selectivity and efficiency (Xie, Wang, Deng, & Luo, 2020).

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