CAS:1268524-69-1 | (±)-JQ1

Introduction of CAS:1268524-69-1 | (±)-JQ1

LSM-6732 is an organonitrogen heterocyclic compound, an organosulfur heterocyclic compound and a tert-butyl ester.

Specification of CAS:1268524-69-1 | (±)-JQ1

Research Application of CAS:1268524-69-1 | (±)-JQ1

Spectroscopic and Quantum Mechanical Study: A study conducted by Kuruvilla et al. (2018) on a similar compound, 4-(2-chlorophenyl)-2-ethyl-9-methyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine, used vibrational spectroscopy and quantum mechanical methods to investigate its properties. The study found that the compound has a lower softness value and high electrophilicity index, which are indicative of its biological activity, potentially as an antidepressant (Kuruvilla, Prasana, Muthu, & George, 2018).

Antagonists for Platelet Activating Factor: Kawakami et al. (1996) explored the structural optimization of 4-(2-chlorophenyl)-9-methyl-6H-thieno[3,2-f]-[1,2,4]triazolo[4,3-a][1,4]diazepine derivatives as antagonists for platelet activating factor. The study highlighted the importance of substituents at the 2- and 6-positions for enhancing affinity for the PAF receptor (Kawakami, Kitani, Yuasa, Abe, Moriwaki, Kagoshima, Terasawa, & Tahara, 1996).

Development of Zein Nanoparticles for Cancer Treatment: A recent study by Celano et al. (2022) discussed the development of zein nanoparticles containing paclitaxel and the compound in question for treating triple-negative breast cancer. The study demonstrated significant in vitro cytotoxic activity against cancer cells, indicating the potential application of this compound in novel nanomedicine (Celano, Gagliardi, Maggisano, Ambrosio, Bulotta, Fresta, Russo, & Cosco, 2022).

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