Introduction and application of CAS No.933041-13-5 | 4-Bromo-6-chloropyridazin-3(2H)-one
4-Bromo-6-chloropyridazin-3(2H)-one is a glycosylation inhibitor and nucleoside analog that can be used in the treatment of cancer. It inhibits the synthesis of deoxyribonucleotides from ribonucleotides by binding to the enzyme ribonucleotide reductase, which catalyzes the conversion of ribonucleotides to deoxynucleotides.
4-Bromo-6-chloropyridazin-3(2H)-one has been shown to inhibit glycosylation in rat liver cells. This drug also inhibits acetone and glycosidation, which are reactions that produce glucose from amino acids or carbohydrates. The crystallization process is also inhibited by this drug because it prevents the formation of nucleoside crystals, which are involved in DNA replication and cell division.
Synonyms:
5-bromo-3-chloro-1H-pyridazin-6-one;
Specification of CAS No.933041-13-5 | 4-Bromo-6-chloropyridazin-3(2H)-one
|
ITEMS |
SPECIFICATION |
|
CAS |
933041-13-5 |
|
MF |
C4H2BrClN2O |
|
MW |
209.43 |
|
Melting point |
220-222 °C(Solv: ethanol (64-17-5); water (7732-18-5)) |
|
Density |
2.16±0.1 g/cm3(Predicted) |
|
acidity coefficient(pKa) |
8.13±0.60(Predicted) |
Package and transportation of Introduction and application of CAS No.933041-13-5 | 4-Bromo-6-chloropyridazin-3(2H)-one
Package:0.1g,1g,5g,25g,100g,500g,1kg
Transportation: by courier/ by air/ by sea


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