Introduction and application of CAS No.918504-65-1 | PLX4032
PLX4032 comes as a white powder or lumpy powder. Easily soluble in N,N-dimethylacetamide, insoluble in acetone and almost insoluble in water.
Synonyms:
N-(3-(5-(4-Chlorophenyl)-1H-pyrrolo[2,3-B]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonaMide;
PLX4032(VeMurafenib);PLX4032,RG7204,ZELBORAF,RO5185426;R7204;
N-(3-(5-(4-Chlorophenyl)-1H-pyrrolo[2,3-B]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonaM;
VeMurafenib(PLX4032,RG7204);N-[3-[[5-(4-Chlorophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-1-propanesulfonamideVemurafenibPLX4032
Specification of CAS No.918504-65-1 | PLX4032
|
ITEMS |
SPECIFICATION |
|
CAS |
918504-65-1 |
|
MF |
C23H18ClF2N3O3S |
|
MW |
489.92 |
|
Density |
1.46 |
|
acidity coefficient(pKa) |
6.26±0.10(Predicted) |
Package and transportation of Introduction and application of CAS No.918504-65-1 | PLX4032
Package:0.1g,1g,5g,25g,100g,500g,1kg
Transportation: by courier/ by air/ by sea
Related Articles of CAS No.918504-65-1 | PLX4032
The RAF inhibitor PLX4032 inhibits ERK signaling and tumor cell proliferation in a V600E BRAF-selective manner
EW Joseph, CA Pratilas… - Proceedings of the …, 2010 - National Acad Sciences
… Like MEK inhibitors, the RAF inhibitor PLX4032 inhibits the proliferation of BRAF … PLX4032.
MEK inhibitors inhibit ERK phosphorylation in all normal and tumor cells, whereas PLX4032 …
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