Introduction and application of CAS No.773-76-2 | 5,7-Dichloro-8-hydroxyquinoline
5,7-Dichloro-8-hydroxyquinoline (5,7-DC8HQ) is a mitochondrial drug that inhibits mitochondrial functions by binding to the ATP synthase. It has been shown to be effective against bacteria resistant to antimicrobial agents in vivo and also showed genotoxic activity in vitro. 5,7-DC8HQ binds to the magnesium site of the ATP synthase protein and prevents the formation of an intramolecular hydrogen bond, which leads to inhibition of ATP synthesis. This drug has also been shown to cause membrane potential depolarization in mitochondria.
Synonyms:
5,7-Dichlor-8-hydroxychinolin;
5,7-Dichloro-8-hydroquinoline;
5,7-Dichloro-8-hydroxyquinolin;
5,7-Dichloro-8-oxychinolin;
5,7-Dichloro-8-oxyquinoline;
5,7-dichloro-8-quinolino;
5,7-Dichlorooxine;5,7-Dichloroxine
Specification of CAS No.773-76-2 | 5,7-Dichloro-8-hydroxyquinoline
|
ITEMS |
SPECIFICATION |
|
CAS |
773-76-2 |
|
MF |
C9H5Cl2NO |
|
MW |
214.05 |
|
Melting point |
178-180 °C (lit.) |
|
Boiling point |
305.47°C (rough estimate) |
|
Density |
1.3320 (rough estimate) |
|
acidity coefficient(pKa) |
2.30±0.30(Predicted) |
Package and transportation of Introduction and application of CAS No.773-76-2 | 5,7-Dichloro-8-hydroxyquinoline
Package:0.1g,1g,5g,25g,100g,500g,1kg
Transportation: by courier/ by air/ by sea
Related Articles of CAS No.773-76-2 | 5,7-Dichloro-8-hydroxyquinoline
Solid–Liquid Equilibrium of 5-Chloro-8-hydroxyquinoline and 5, 7-Dichloro-8-hydroxyquinoline in Different Solvents and Mixing Properties of Solutions
Z Yang, D Shao, G Zhou - Journal of Chemical & Engineering …, 2019 - ACS Publications
… temperatures of 5-chloro-8-hydroxyquinoline and 5,7-dichloro-8-hydroxyquinoline in this …
The thermograms of 5,7-dichloro-8-hydroxyquinoline in the Supporting Information (Figure …
Hot Tags: cas no.773-76-2 | 5,7-dichloro-8-hydroxyquinoline, China cas no.773-76-2 | 5,7-dichloro-8-hydroxyquinoline manufacturers, factory, Tetrahydrofurfuryl alcohol, Ocimene, Spermidine, Other Material Chemicals, Alpha Methyls Styrene Dimer, Epsilon-polylysine
