Introduction and application of CAS No.156-81-0 | 2,4-Diaminopyrimidine
2,4-Diaminopyrimidine is a potent inhibitor of protein kinases with selectivity for ATP-dependent enzymes. It inhibits the activity of the epidermal growth factor receptor (EGFR). The effectiveness of 2,4-diaminopyrimidine against colorectal adenocarcinoma cells has been demonstrated in vitro and in vivo.
The drug has been shown to inhibit EGFR phosphorylation and downstream signaling pathways, which may be responsible for its ability to induce apoptosis in these cancer cells. 2,4-Diaminopyrimidine has also been shown to have anti-inflammatory effects by inhibiting the production of proinflammatory cytokines and chemokines. This drug is used in clinical studies as an anti-infective agent against infectious diseases such as tuberculosis, malaria, and dengue fever.
2,4-Diaminopyrimidine is a diaminopyrimidine.
Synonyms:
diamino-pyrimidine;
2,4-Pyrimidinediamine;
DAP;
Pyrimidine-2,4-diamine;
2,4-diamino-pyrimidine;
pyrimidinediamine;
2,6-DIAMINOPYRIMIDINE;
pyrimidine-2,4-diyldiamine;
Pyrimidine,2,4-diamino;
Specification of CAS No.156-81-0 | 2,4-Diaminopyrimidine
|
ITEMS |
SPECIFICATION |
|
CAS |
156-81-0 |
|
MF |
C4H6N4 |
|
MW |
110.12 |
|
Melting Point |
143-147 °C (lit.) |
|
Boiling point |
401.7±37.0 °C(Predicted) |
|
Density |
1.368±0.06 g/cm3(Predicted) |
|
Refractive Index |
1.46-1.466 |
|
Flash Point |
225.6ºC |
Package and transportation of Introduction and application of CAS No.156-81-0 | 2,4-Diaminopyrimidine
Package:0.1g,1g,5g,25g,100g,500g,1kg
Transportation: by courier/ by air/ by sea


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