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CAS No.156-81-0 | 2,4-Diaminopyrimidine

CAS No.156-81-0 | 2,4-Diaminopyrimidine

Name:2,4-Diaminopyrimidine
CAS No.156-81-0
MF:C4H6N4
MW:110.12
Purity:97%
EINECS:205-862-3
Appearance:white to almost white powder
Package: 5g,25g,100g,500g,1kg,25kg
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Product Introduction

Introduction and application of CAS No.156-81-0 | 2,4-Diaminopyrimidine

 

2,4-Diaminopyrimidine is a potent inhibitor of protein kinases with selectivity for ATP-dependent enzymes. It inhibits the activity of the epidermal growth factor receptor (EGFR). The effectiveness of 2,4-diaminopyrimidine against colorectal adenocarcinoma cells has been demonstrated in vitro and in vivo.

 

The drug has been shown to inhibit EGFR phosphorylation and downstream signaling pathways, which may be responsible for its ability to induce apoptosis in these cancer cells. 2,4-Diaminopyrimidine has also been shown to have anti-inflammatory effects by inhibiting the production of proinflammatory cytokines and chemokines. This drug is used in clinical studies as an anti-infective agent against infectious diseases such as tuberculosis, malaria, and dengue fever.

 

2,4-Diaminopyrimidine is a diaminopyrimidine.

 

Synonyms:

diamino-pyrimidine;

2,4-Pyrimidinediamine;

DAP;

Pyrimidine-2,4-diamine;

2,4-diamino-pyrimidine;

pyrimidinediamine;

2,6-DIAMINOPYRIMIDINE;

pyrimidine-2,4-diyldiamine;

Pyrimidine,2,4-diamino;

 

Specification of CAS No.156-81-0 | 2,4-Diaminopyrimidine

ITEMS

SPECIFICATION

CAS

156-81-0

MF

C4H6N4

MW

110.12

Melting Point

143-147 °C (lit.)

Boiling point

401.7±37.0 °C(Predicted)

Density

1.368±0.06 g/cm3(Predicted)

Refractive Index

1.46-1.466

Flash Point

225.6ºC

 

Package and transportation of Introduction and application of CAS No.156-81-0 | 2,4-Diaminopyrimidine

Package:0.1g,1g,5g,25g,100g,500g,1kg

Transportation: by courier/ by air/ by sea

 

product-696-396

product-706-367

 

Related Articles of CAS No.156-81-0 | 2,4-Diaminopyrimidine

Cu (I)–I-2, 4-diaminopyrimidine coordination polymers with optoelectronic properties as a proof of concept for solar cells

J López, JG Platas, UR Rodríguez-Mendoza… - Inorganic …, 2020 - ACS Publications

… Compounds 1 and 2 can be obtained by a direct synthesis between CuI and the 2,4-diaminopyrimidine

in acetonitrile and acetonitrile–ethanol at room temperature. These synthetic …

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