Introduction and application of CAS 5852-78-8 | 5-Carboxy-8-hydroxyquinoline
5JMJD2 is an enzyme that catalyzes the methylation of histone H3 at lysine 27. JMJD2 inhibitors are compounds that inhibit JMJD2 activity, which may be used to treat cancer. This class of drugs inhibits the activity of JMJD2 by binding to the active site and blocking the substrate from entering. The most potent compound in this class, 5-carboxy-8HQ, has been shown to have antibacterial efficacy in a squamous cell carcinoma model system and up-regulated expression in wild-type cells. Additionally, this compound has been shown to significantly inhibit tumor growth in a mouse model of atherosclerotic lesion.
Synonyms:
8-Hydroxy-chinolin-5-carbonsaeure;
8-hydroxy-quinoline-5-carboxylicacid;
UNII-JM015YQC1C;
5-Carboxy-8-hydroxyquinoline;
Specification of CAS 5852-78-8 | 5-Carboxy-8-hydroxyquinoline
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ITEMS |
SPECIFICATION |
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CAS |
5852-78-8 |
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Appearance |
Powder |
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MF |
C10H7NO3 |
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MW |
189.16700 |
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Boiling point |
464.5±30.0 °C(Predicted) |
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Density |
1.480±0.06 g/cm3 |
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Refractive index |
1.545 |
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Storage condition |
2-8°C |
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Flash Point |
304 (exp.) |
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Package and transportation of CAS 5852-78-8 | 5-Carboxy-8-hydroxyquinoline
Package:25g,100g,500g,1kg,5kg,50kg
Transportation: by courier/ by air/ by sea
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