CAS No.956104-40-8 | Apalutamide

Introduction and application of CAS No.956104-40-8 | Apalutamide

A potent antagonist of androgen receptor with IC₅₀ value of 16 nM. Binds androgen receptors, thereby inhibiting nuclear translocation, DNA binding and transcriptional activation. Has therapeutic applications in non-metastatic, castration-resistant prostate cancer.

Synonyms:

ARN-509;

4-(7-(6-cyano-5-(trifluoroMethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspirooctan-5-yl)-2-fluoro-N-MethylbenzaMide;

AR509;Benzamide,4-[7-[6-cyano-5-(trifluoromethyl)-3-pyridinyl]-8-oxo-6-thioxo-5,7-diazaspiro[3.4]oct-5-yl]-2-fluoro-N-methyl-;

4-[7-[6-Cyano-5-(trifluoromethyl)pyridin-3-yl]-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl]-2-fluoro-N-methylbenzamideARN-509;

AR509100G;4-[7-[6-Cyano-5-(trifluoromethyl)pyridin-3-yl]-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl]-2-fluoro-N-methylbenzamide;

Specification of CAS No.956104-40-8 | Apalutamide

Package and transportation of Introduction and application of CAS No.956104-40-8 | Apalutamide

Package:0.1g,1g,5g,25g,100g,500g,1kg

Transportation: by courier/ by air/ by sea

Related Articles of CAS No.956104-40-8 | Apalutamide

[HTML] Apalutamide and overall survival in prostate cancer

MR Smith, F Saad, S Chowdhury, S Oudard… - European urology, 2021 - Elsevier

… apalutamide group than in the placebo group (apalutamide, 32.9 mo; placebo, 11.5 mo).

Median treatment duration with apalutamide … was similar between the apalutamide and placebo …

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