Introduction of CAS:922518-84-1 | 4,4,5,5-tetraMethyl-2-[10-(2-phthalenyl)-9-anthracenyl]-1,3,2-Dioxaborolane
The compound "4,4,5,5-Tetramethyl-2-(10-(naphthalen-2-yl)anthracen-9-yl)-1,3,2-dioxaborolane" is an anthracene compound in which an aryl group having C10 or greater is bonded to the 9-position and a naphthyl group is bonded to the 10-position.
The physical and chemical properties of this compound include a high GI absorption, BBB permeant, and it is an inhibitor of CYP1A2 and CYP2D6. It has a moderately soluble water solubility.
Specification of CAS:922518-84-1 | 4,4,5,5-tetraMethyl-2-[10-(2-phthalenyl)-9-anthracenyl]-1,3,2-Dioxaborolane
|
ITEMS |
SPECIFICATION |
|
Melt point |
214 °C |
|
Purity |
97% |
|
Form |
powder crystal |
|
Color |
White to light yellow to light orange |
Research Application of CAS:922518-84-1 | 4,4,5,5-tetraMethyl-2-[10-(2-phthalenyl)-9-anthracenyl]-1,3,2-Dioxaborolane
Synthesis and Application in Drug Development
4,4,5,5-Tetramethyl-2-(10-(naphthalen-2-yl)anthracen-9-yl)-1,3,2-dioxaborolane has been used as a building block for synthesizing biologically active derivatives. For instance, it played a crucial role in the alternative synthesis of the retinoid agonist disila-bexarotene, demonstrating its potential in drug development (Büttner et al., 2007).
Electroluminescence and OLED Applications
This compound is instrumental in developing blue-emitting materials for organic light-emitting diodes (OLEDs). Various studies have explored its use in synthesizing materials like Na-AP-Na, which exhibited high device efficiency and good blue color coordinates for displays (Lee et al., 2014). Additionally, it has been utilized in creating new anthracene derivatives with coumarin moiety for OLEDs, contributing to non-doped OLEDs with significant luminescence efficiency (Jung et al., 2017).
Organic Synthesis and Chemical Studies
Its use extends to the synthesis of other complex organic compounds. For example, it was essential in preparing 2-ruthenocenyl-4,4,5,5-tetramethyl-1,3-dioxa-2-borolane for studying the redox behaviors of binuclear ruthenocene derivatives (Sato et al., 2002). Also, it was used in developing diborylated naphtho[1,2-c:5,6-c′]bis[1,2,5]thiadiazole, demonstrating its role in synthesizing high-performance semiconducting polymers (Kawashima et al., 2013).
Biochemical Applications
In biochemical research, this compound has been employed in studying the selective delivery of polyamine conjugates into cells with active polyamine transporters. Its structural variations have been explored to understand the limits of substituents accommodated by the polyamine transporter (Gardner et al., 2004).



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