Introduction and application of CAS No.850568-62-6 | 5-BENZYLOXY-1-BOC-INDOLE-2-BORONIC ACID
5-Benzyloxy-1H-indole-2-boronic acid, N-BOC protected is a potent and selective inhibitor of aurora kinase A (AuroraA) with IC50 of about 20 nM. AurorA is a serine/threonine kinase that regulates cell cycle progression, transcription, DNA repair, and other cellular processes.
Synonyms:
[1-[(2-methylpropan-2-yl)oxycarbonyl]-5-phenylmethoxyindol-2-yl]boronic acid;
5-Benzyloxy-1H-indole-2-boronic acid, N-BOC protected;
5-BENZYLOXY-1-BOC-INDOLE-2-BORONIC ACID;
5-Benzyloxyindole-2-boronic acid,N-BOC protected;
2-borono-5-benzyloxy-indole-1-carboxylic acid tert-butyl ester;
1-tert-butyloxycarbonyl-5-benzyloxy-indole-2-boronic acid;
1-boc-indole-5-benzyloxy-2-boronic acid;
5-Benzyloxy-1H-indole-2-boronic acid,N-BOC protected;
Specification of CAS No.850568-62-6 | 5-BENZYLOXY-1-BOC-INDOLE-2-BORONIC ACID
|
ITEMS |
SPECIFICATION |
|
CAS |
850568-62-6 |
|
MF |
C20H22BNO5 |
|
MW |
367.2 |
|
Melting point |
106-110ºC |
|
Boiling point |
564.7±60.0 °C(Predicted) |
|
Density |
1.17±0.1 g/cm3(Predicted) |
|
acidity coefficient(pKa) |
7.97±0.30(Predicted) |
|
Storage |
2-8°C |
Package and transportation of Introduction and application of CAS No.850568-62-6 | 5-BENZYLOXY-1-BOC-INDOLE-2-BORONIC ACID
Package:0.1g,1g,5g,25g,100g,500g,1kg
Transportation: by courier/ by air/ by sea


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… -indole-2-boronic acid afforded 6 in good yield when Pd(dppf)Cl 2 was used as the catalyst.
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