![CAS No.1919837-50-5 | 2-[1-(Ethanesulfonyl)-3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]azetidin-3-yl]acetonitrile](/uploads/202340266/cas-no-1919837-50-5-2-1-ethanesulfonyl-3-4-402b9b1dc-f7ea-4a0a-85bf-b969f2d85bcc.jpg)
![CAS No.1919837-50-5 | 2-[1-(Ethanesulfonyl)-3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]azetidin-3-yl]acetonitrile](/uploads/202340266/cas-no-1919837-50-5-2-1-ethanesulfonyl-3-4-42edde44a-4f8d-46ab-9788-f3f89c6a2d94.jpg)
![CAS No.1919837-50-5 | 2-[1-(Ethanesulfonyl)-3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]azetidin-3-yl]acetonitrile](/uploads/202340266/cas-no-1919837-50-5-2-1-ethanesulfonyl-3-4-47127a955-0d5a-47ae-8c28-f841aa188160.png)
Introduction and application of CAS No.1919837-50-5 | 2-[1-(Ethanesulfonyl)-3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]azetidin-3-yl]acetonitrile
2-[1-(Ethanesulfonyl)-3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]azetidin-3-yl]acetonitrile is a potent and selective inhibitor of programmed cell death protein 1 (PD-L1). PD-L1 is an immune checkpoint protein that interacts with the PD1 receptor on T cells to inhibit T cell activation. 2-[1-(Ethanesulfonyl)-3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H pyrazol]-azetidin]-acetonitrile binds to the PDL receptor and blocks its interaction with the PD1 receptor.
Synonyms:
3-Azetidineacetonitrile, 1-(ethylsulfonyl)-3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]-;
Specification of CAS No.1919837-50-5 | 2-[1-(Ethanesulfonyl)-3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]azetidin-3-yl]acetonitrile
|
ITEMS |
SPECIFICATION |
|
CAS |
1919837-50-5 |
|
MF |
C16H25BN4O4S |
|
MW |
380.27 |
|
Boiling Point |
572.6±60.0 °C(Predicted) |
|
Density |
1.27±0.1 g/cm3(Predicted) |
|
acidity coefficient (pKa)
|
2.63±0.19(Predicted) |
Package and transportation of Introduction and application of CAS No.1919837-50-5 | 2-[1-(Ethanesulfonyl)-3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]azetidin-3-yl]acetonitrile
Package:0.1g,1g,5g,25g,100g,500g,1kg
Transportation: by courier/ by air/ by sea
Hot Tags: cas no.1919837-50-5 | 2-[1-(ethanesulfonyl)-3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1h-pyrazol-1-yl]azetidin-3-yl]acetonitrile, China cas no.1919837-50-5 | 2-[1-(ethanesulfonyl)-3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1h-pyrazol-1-yl]azetidin-3-yl]acetonitrile manufacturers, factory, Methyltin mercaptide, Chemical Reagents
