CAS:76578-79-5 | 6-CHLORO-2-[(4-HYDROXYPHENYL)OXY]QUINOXALINE

Introduction of CAS:76578-79-5 | 6-CHLORO-2-[(4-HYDROXYPHENYL)OXY]QUINOXALINE

"4-(6-Chloroquinoxalin-2-yloxy)phenol" is a chemical compound with the molecular formula C14H9ClN2O2 . It has an average mass of 272.686 Da and a monoisotopic mass of 272.035248 Da . This compound is also known by other names such as "6-CHLORO-2-[(4-HYDROXYPHENYL)OXY]QUINOXALINE" and "Phenol, 4-[(6-chloro-2-quinoxalinyl)oxy]" .

Specification of CAS:76578-79-5 | 6-CHLORO-2-[(4-HYDROXYPHENYL)OXY]QUINOXALINE

Research Application of CAS:76578-79-5 | 6-CHLORO-2-[(4-HYDROXYPHENYL)OXY]QUINOXALINE

Nucleophilic Substitution and Antibacterial Activity

4-(6-Chloroquinoxalin-2-yloxy)phenol is used in nucleophilic substitution reactions, particularly in the synthesis of phenoxychloroquinoxaline derivatives. These derivatives have demonstrated antibacterial activity, indicating potential applications in medicinal chemistry and drug development (Babu & Srinivasu, 2021).

Crystal Structure Analysis

This compound has been studied for its crystal structure, specifically in its application as a herbicide. Understanding the crystal structure is crucial for optimizing the efficacy and safety of such compounds in agricultural applications (Jeon, Kim, Lee & Kim, 2014).

Synthesis and Antimicrobial Activity

Various derivatives of this compound have been synthesized and tested for their antimicrobial properties. This research contributes to the development of new antimicrobial agents and helps in understanding the relationship between chemical structure and biological activity (Singh, Deivedi, Hashim & Singhal, 2010).

Aldose Reductase Inhibitors and Antioxidant Activity

Derivatives based on this compound have been studied for their potential as aldose reductase inhibitors, which are important in managing complications of diabetes. Additionally, these derivatives exhibit antioxidant properties, which could be beneficial in treating oxidative stress-related disorders (Hao, Han, Li, Li, Wang, Zhang, Yang, Ma & Zhu, 2017).

Environmental Degradation

Research has also been conducted on the degradation of phenolic compounds like this compound by microorganisms such as Rhodococcus opacus. This is important for understanding the environmental impact and biodegradation processes of these compounds (Kitagawa, Kimura & Kamagata, 2004).

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