Introduction of CAS:58888-76-9 | 3-HYDROXY-3-METHYLHEXANOIC ACID
Synthesis Analysis
The synthesis of 3-Hydroxy-3-methylhexanoic acid and its derivatives involves complex chemical pathways that have been explored in various studies. These pathways often involve the strategic manipulation of molecular structures to achieve the desired compound. For instance, the microbial production of related hydroxy acids from CO2 showcases innovative methods of synthesis, highlighting the potential for sustainable production processes (Ishizaki, Tanaka, & Taga, 2001).
Molecular Structure Analysis
The molecular structure of 3-Hydroxy-3-methylhexanoic acid is crucial in determining its chemical behavior and reactivity. The presence of hydroxy groups and their position within the molecule significantly influence its properties and interactions. Studies on hydroxycinnamic acids have revealed how structural variations can impact antioxidant activity, providing insights into the importance of molecular structure in determining the compound's functionality (Razzaghi-Asl et al., 2013).
Chemical Reactions and Properties
3-Hydroxy-3-methylhexanoic acid participates in a variety of chemical reactions, leading to the formation of diverse derivatives with unique properties. For example, the conversion processes involving hydroxycitric acid, a compound with similarities to 3-Hydroxy-3-methylhexanoic acid, demonstrate the compound's versatility and potential for producing biologically active molecules (Yamada, Hida, & Yamada, 2007).
Specification of CAS:58888-76-9 | 3-HYDROXY-3-METHYLHEXANOIC ACID
|
ITEMS |
SPECIFICATION |
|
Density |
1.344±0.06 g/cm3(Predicted) |
|
Boiling point |
1.072±0.06 g/cm3(Predicted) |
|
Color |
Colorless to pale yellow |
|
Form |
oily |
|
Storage condition |
Sealed in dry,Room Temperature |
Research Application of CAS:58888-76-9 | 3-HYDROXY-3-METHYLHEXANOIC ACID
Monitoring System for Underarm Odor
A study by Hirano, Isomura, and Futagawa (2018) developed a novel system to monitor underarm odor by measuring the pH and electrical conductivity of 3-Hydroxy-3-methylhexanoic acid. This approach offers potential in understanding and controlling underarm odor by monitoring its causative agents on the skin (Hirano, Isomura & Futagawa, 2018).
Analytical Method for Biomarker Detection
Dallo et al. (2016) presented an analytical method involving solid-phase microextraction and gas chromatography with mass spectrometry to detect 3-Hydroxy-3-methylhexanoic acid as a biomarker in human sweat in environmental samples. This method aids in the understanding of human odor diffusion processes (Dallo et al., 2016).
Olfactory Perception and Social Functioning
Sorokowska et al. (2021) explored the perception of 3-Hydroxy-3-methylhexanoic acid (HMHA) in relation to social functioning. The study examined whether HMHA-specific anosmia (inability to perceive HMHA) predicts loneliness and social withdrawal, providing insights into the role of specific odor components in social interactions (Sorokowska et al., 2021).
Production of Polyhydroxyalkanoate Copolymers
Research by Furutate et al. (2017) investigated the biosynthesis of novel polyhydroxyalkanoate copolymers involving 3-Hydroxyhexanoate (a related compound). This study highlights the potential use of 3-Hydroxy-3-methylhexanoic acid derivatives in the production of biodegradable plastics and materials (Furutate et al., 2017).
Differentiation of Mesenchymal Stem Cells
Wang et al. (2010) conducted a study on the differentiation of human bone marrow mesenchymal stem cells into nerve cells using scaffolds made of polyhydroxyalkanoates, which may include derivatives of 3-Hydroxy-3-methylhexanoic acid. This research contributes to the field of tissue engineering and regenerative medicine (Wang et al., 2010).
Profiling of Endotoxin Markers
A study by Uhlig et al. (2016) profiled 3-Hydroxy fatty acids, including 3-Hydroxy-3-methylhexanoic acid, as chemical markers of endotoxin. This approach is significant in assessing environmental and occupational exposure to endotoxins (Uhlig et al., 2016).


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