Introduction and application of CAS 1427004-19-0 | DBCO-PEG4-NHS ester
Dibenzocyclooctyne-PEG4-N-hydroxysuccinimidyl ester (DBCO-PEG4-NH2) is a water soluble, biodegradable and biocompatible polymer that is used to synthesize nanoparticles with a diameter of ˜100 nm.
These particles have high uptake by cells in vitro and can be used for the treatment of cancer. DBCO-PEG4-NH2 has shown to be cytotoxic to mouse tumor cells in vitro and has been shown to induce cell death through apoptosis, which may be due to its ability to activate factor receptors.
Synonyms:
DBCO-PEG4-succinimidyl ester
DBCO-PEG4-NHS ester
DBCO-PEG4-SE
Specification of CAS 1427004-19-0 | DBCO-PEG4-NHS ester
|
ITEMS |
SPECIFICATION |
|
CAS |
1427004-19-0 |
|
MF |
C34H39N3O10 |
|
MW |
649.69 |
|
Density |
1.33±0.1 g/cm3(Predicted) |
|
Storage |
-20°C |
|
solubility |
Soluble in DMSO, DCM, DMF |
|
acidity coefficient(pKa) |
15.14±0.46(Predicted) |
Package and transportation of Introduction and application of CAS 1427004-19-0 | DBCO-PEG4-NHS ester
Package:100mg,250mg,500mg,1g,5g,25g,100g
Transportation: by courier/ by air/ by sea
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… Increasing the concentration of linker DBCO-PEG4-NHS ester to 0.5 mM for antibody
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