CAS: 1403744-37-5 | DSPE-PEG-COOH

Introduction and application of CAS: 1403744-37-5 | DSPE-PEG-COOH

SPE-PEG-COOH is a linear heterobifunctional pegylation reagent containing DSPE phospholipids and carboxylic acids. It is a useful self-assembly reagent for the preparation of PEGylated liposomes or micelles while providing COOH groups for conjugation with amine-containing molecules. It is commonly used for targeted drug delivery in lipid bilayers to improve drug solubility, PEG provides stealth properties, extends circulation half-life and reduces non-specific protein binding or cell adhesion, and for bioconjugation of targeting molecules including antibodies , aptamers, proteins and peptides).

Structural formula:

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