Introduction of CAS:1301205-62-8 | (3-BROMONAPHTHALEN-2-YL)BORONIC ACID
(3-Bromonaphthalen-2-yl)boronic acid is an important chemical compound that has gained significant attention in the field of organic chemistry. It is a boronic acid derivative that contains a naphthalene ring with a bromine atom attached to it. This compound has shown potential in various scientific research applications, including drug discovery, catalysis, and materials science.
Specification of CAS:1301205-62-8 | (3-BROMONAPHTHALEN-2-YL)BORONIC ACID
|
ITEMS |
SPECIFICATION |
|
Purity |
98% |
|
Acidity coefficient (pKa) |
6.99±0.30(Predicted) |
|
Density |
1.62±0.1 g/cm3(Predicted) |
|
Boiling point |
434.4±47.0 °C(Predicted) |
Research Application of CAS:1301205-62-8 | (3-BROMONAPHTHALEN-2-YL)BORONIC ACID
Synthesis of Chiral 1,1'-Binaphthalenes
(3-Bromonaphthalen-2-yl)boronic acid is crucial in the synthesis of chiral 1,1'-binaphthalenes through the asymmetric Suzuki-Miyaura reaction. The synthesis is significantly improved by simple purification of naphthylboronic acids before use in coupling reactions. This method provides convenient access to chiral sterically hindered binaphthalene derivatives, which are important in various applications, including the development of new materials and drugs (Genov, Almorín, & Espinet, 2006).
Fluorescent Chemosensors
Boronic acids, including (3-Bromonaphthalen-2-yl)boronic acid, are used in the development of fluorescent chemosensors. These sensors can detect biological substances crucial for disease prevention, diagnosis, and treatment. They interact with cis-1,2- or 1,3-diol to form cyclic structures, which can be used as fluorescent reporters to probe carbohydrates and other bioactive substances (Huang et al., 2012).
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