Introduction and application of CAS 122111-01-7 | 2-Deoxy-2,2-difluoro-D-erythro-pentafuranous-1-ulose-3,5-dibenzoate
2-Deoxy-2,2-difluoro-D-erythro-pentafuranous-1-ulose-3,5-dibenzoate (3,5-Di-O-benzoyl-2-deoxy-2,2-difluoro-D-ribonic acid-1,4-lactone (3DBR)) is a nucleoside that has been shown to have antiaging properties. It has been found to be an effective scavenger of peroxyl radicals and reactive oxygen species (ROS).
3DBR also inhibits the formation of aluminum oxide and styrene by catalyzing the salt formation reaction. This compound also has anti-tumour activity and can be used as a chemotherapeutic agent for the treatment of cancer. It is heat resistant and can be combined with gemcitabine hydrochloride in chemotherapy.
Synonyms:
2-Deoxy-2,2-difluoro-<small>D</small>-<i>erythro</i>-pentonic Acid γ-Lactone 3,5-Dibenzoate;
((2R,3R)-3-(Benzoyloxy)-4,4-difluoro-5-oxotetrahydrofuran-2-yl)methyl benzoate;
2-Deoxyl-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate;
2-Deoxy-2,2-Difluoro-d-Erythro-Pentofuranos-1-Ulose-3,5-Dibenzoate;
[(2R,3R)-3-benzoyloxy-4,4-difluoro-5-oxooxolan-2-yl]methyl benzoate;
2-Deoxy-2,2-difluoro-D-erythro-pentonic acid γ-Lactone 3,5-dibenzoate;
Specification of CAS 122111-01-7 | 2-Deoxy-2,2-difluoro-D-erythro-pentafuranous-1-ulose-3,5-dibenzoate
|
ITEMS |
SPECIFICATION |
|
CAS |
122111-01-7 |
|
MF |
C19H14F2O6 |
|
MW |
376.31 |
|
Melting point |
117-119 °C(lit.) |
|
Boiling point |
437.2±45.0 °C(Predicted) |
|
Density |
1.41±0.1 g/cm3(Predicted) |
|
Solubility |
Chloroform (Slightly), Methanol (Slightly) |
Package and transportation of Introduction and application of CAS 122111-01-7 | 2-Deoxy-2,2-difluoro-D-erythro-pentafuranous-1-ulose-3,5-dibenzoate
Package:0.1g,1g,5g,25g,100g,500g,1kg
Transportation: by courier/ by air/ by sea
Related Articles of CAS 122111-01-7 | 2-Deoxy-2,2-difluoro-D-erythro-pentafuranous-1-ulose-3,5-dibenzoate
Syntheses of 5′-amino-2′, 5′-dideoxy-2′, 2′-difluorocytidine derivatives as novel anticancer nucleoside analogs
MA Labroli, MP Dwyer, R Shen, J Popovici-Muller… - Tetrahedron …, 2014 - Elsevier
… 2-deoxyl-2,2-difluoro-d-erythro-pentafuranous-1-ulose-3,5-dibenzoate (11) (Scheme 3). …
followed by hydrolysis of the 3′,5′-dibenzoate under mild basic conditions to provide diol 13. …
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